Philip Demokritou

Philip Demokritou

Associate Professor of Aerosol Physics
Director of the Environmental Health Nanoscience Laboratory and the Center for Nanotechnology and Nanotoxicology at Harvard T.H. Chan School of Public Health
Philip Demokritou

Research Interests

Dr. Demokritou's research interests are primarily in the areas of aerosol science and technology and particle health effects. His current research focuses on the applications and environmental health and safety implications of engineered nanomaterials and nanotechnology in general. Dr. Demokritou has been one of the PI's of the Harvard/US EPA Center for Ambient Particle Health Effects and participated in many international Particle Health Effect field studies (US, Chile, Finland, Greece, Kuwait, Cyprus). Dr. Demokritou and his team have developed over the years many instruments and patented methods focusing on the physico-chemical and biological characterization of particles. These novel techniques have been used extensively by human exposure assessors in United States and worldwide and helped to advance the field of particle health effects. Dr. Demokritou also led the efforts of Harvard School of Public Health at international level and help establishing graduate level Environmental Health Programs in Europe (Cyprus). He is a co-author of two books, book chapters and numerous articles in leading journals in the particle health effect and aerosol engineering fields. He is currently the Director of the Environmental Health Nanoscience Laboratory and the Center for Nanotechnology and Nanotoxicology at the Harvard School of Public Health.

Related Publications

Pirela S., Molina R., Watson C, Cohen L., Bello D., Brain J., Demokritou P. Effects of copy center particles on the lungs: A toxicological characterization using a Balb/c mice model. Inhalation Toxicology, in press, 2013

Gass S., Cohen J., Pyrgiotakis G., Sotiriou G., Pratsinis S., Demokritou P. A safer formulation concept for flame generated nanomaterials. ACS. Sus. Chem. Eng. 2013, DOI: 10.1021/sc300152f

Demokritou P, Gass S., Pyrgiotakis G, Cohen J., Goldsmith W., McKinney W., Frazer D, Ma J., Schwegler-Berry D., Brain J., Castranova V. An in vivo and in vitro toxicological characterization of realistic nanoscale CeO2 inhalation exposures. Nanotoxicology 2012, DOI: 10.3109/17435390.2012.739665

Chang C, Demokritou, P., Shafer M. and Christiani D. Physicochemical and toxicological characteristics of welding fume derived particles generated from real time welding processes. Journal of Environmental Monitoring, 2012, DOI: 10.1039/c2em30505d

Pyrgiotakis G., McDevitt J., Yamauchi T., Demokritou P. A novel method for bacteria inactivation using electrosprayed water nanostructures. Journal of Nanoparticle Research 2012; vol.14, number 8, DOI: 10.1007/s11051-012-1027-x

Bello D, Martin J, Santeufemio C., Sun Q., Bunker K., Shafer M. and Demokritou P. Physico-chemical and morphological characterization of nanoparticles emitted from photocopiers: Implications for Environmental Health. Nanotoxicology 2012, DOI: 10.3109/17435390.2012.689883.

Cohen J, DeLoid G, Pyrgiotakis G, Demokritou P. Interactions of engineered nanomaterials in physiological media and the implications for in vitro dosimetry. Nanotoxicology 2012, DOI: 10.3109/17435390.2012.666576.

Tsai S, Echevarría-Vega E,2, Sotiriou G, Santeufemio C, Huang C, Schmidt D, Demokritou P, Ellenbecker M. Evaluation of environmental filtration control of engineered nanoparticles using the Harvard Versatile Engineered Nanomaterial Generation System (VENGES). Journal of Nanoparticle Research 2012, DOI 10.1007/s11051-012-0812-x

Sotiriou G., Diaz E., Godleski J., Brain J., Pratsinis S., Demokritou P. A novel method for inhalation toxicological characterization of engineered nanomaterials. Nanotoxicology 2011, DOI: 10.3109/17435390.2011.604439, 2011.

Zhu S., Srebric J., Spengler J. and Demokritou P. An advanced numerical model for the assessment of airborne transmission of influenza in bus microenvironments. Building and Environment 2011; 47: 67-75.

Demokritou P, B├╝chel R, Molina R, Deloid G, Brain J, Pratsinis S. Development and characterization of a Versatile Engineered Nanomaterial Generation System (VENGES) suitable for toxicological studies. Inhalation Toxicology 2010; 22: 107-116.

Zhu S, Demokritou P and Spengler J. Experimental and numerical investigation of micro-environmental conditions in public transportation buses. Building and Environment 2010; 45: 2077-2088.

Middleton N, Yiallouros P, Nicolaou N, Kleanthous S, Pipis S, Zeniou M, Demokritou P, Koutrakis P. Residential exposure to motor vehicle emissions and the risk of wheezing among 7-8 year-old schoolchildren: a city-wide cross-sectional study in Nicosia, Cyprus. Environmental Health 2010; 9(28): DOI: 10.1186/1476-069X-9-28

Middleton N, Yiallouros P, Kleanthous S, Kolokotroni O, Schwartz J, Dockery D, Demokritou P, Koutrakis P. A 10-year time-series analysis of respiratory and cardiovascular morbidity in Nicosia, Cyprus: The effect of short-term changes in air pollution and dust storms, 1994-2004. Environmental Health 2008; 7: DOI: 10.1186/1476-069X-7-3.

Lee S, Demokritou P, Koutrakis P, Delgado-Saborit J. Development and Evaluation of a personal respirable particulate sampler (PRPS). Atmospheric Environment 2006; 40: 212-224.

Lee S, Demokritou P, Koutrakis P. Performance evaluation of commonly used impaction substrates under various loading conditions. Journal of Aerosol Science 2005; 36: 881-895.

Koutrakis P, Sax SN, Sarnat JA, Coull B, Demokritou P, Oyola P, Garcia J, Gramsch E. Analysis of PM10, PM2.5, and PM2.5-10 concentrations in Santiago, Chile, from 1989 to 2001. Journal of Air and Waste Management Association 2005; 55: 342-351.

Gupta T, Demokritou P, Koutrakis P. Effects of physico-chemical properties of ultrafine particles on the performance of an ultrafine particle concentrator. Aerosol Science and Technology 2004; 38: 37-45.

Gupta T, Demokritou P, Ferguson S, Koutrakis P. Development and performance evaluation of a high-volume ultrafine particle concentrator for inhalation toxicological studies. Inhalation Toxicology 2004; 16: 851-862.

Demokritou P, Lee SJ, Koutrakis P. Development and evaluation of a high loading PM2.5 speciation sampler. Aerosol Science and Technology 2004; 38: 111-119.

Demokritou P, Lee SJ, Koutrakis P. A compact multistage (cascade) impactor for the characterization of atmospheric aerosols. Journal of Aerosol Science 2004; 35: 281-299.

Demokritou P, Gupta T, Ferguson S, Koutrakis P. Development of a high-volume concentrated ambient particles system (CAPS) for human and animal inhalation toxicological studies. Inhalation Toxicology 2003;15: 111-129.


Center for Nanotechnology and Nanotoxicology

Contact Information

Building 1, Room 1310B (655 Huntington Avenue, Boston)

Research Areas

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